At present, there are two varieties of research on itaconate: Irg1−/− macrophages along with the regulatory impact of itaconate derivatives. Both of these outcomes had been complementary and disclosed the regulatory mechanisms of itaconate concerned alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription variable 3 (ATF3) induction https://richardj554tep7.blogitright.com/profile